BasicPolarAcidicNonpolarCopper ion
Pal · Lys · Thr · Thr · Lys · Ser
Palmitoyl Pentapeptide-4
Pal-KTTKS · formerly palmitoyl pentapeptide-3
- Origin
- The KTTKS sequence comes from type I procollagen. A 16-carbon palmitoyl chain helps it cross the skin's lipid barrier.
- In studies
- Robinson et al. (2005) ran a 12-week, placebo-controlled trial on photoaged facial skin and saw measurable improvement.
- On market
- Since 2000.
Where the evidence stopsThe effects are modest next to prescription retinoids. Set expectations for gradual change over months.